A systematic review and meta-analysis regarding the use of corticosteroids in septic arthritis
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Chondral damage is one of the major sequelae of septic arthritis; occurring even after prompt treatment of a septic joint. Subsequent loss of joint function can have a significant impact on a patient’s quality of life. Corticosteroids are known to have beneficial effects on the rate and extent cartilage destruction in arthritis through a variety of mediators such as synovial RANKL expression, mast cells and pro-inflammatory cytokines.
Nội dung trích xuất từ tài liệu:
A systematic review and meta-analysis regarding the use of corticosteroids in septic arthritis
Nội dung trích xuất từ tài liệu:
A systematic review and meta-analysis regarding the use of corticosteroids in septic arthritis
Tìm kiếm theo từ khóa liên quan:
BMC Musculoskeletal Disorders Despite modern antibiotic therapy Chondral damage Quality of life Extent cartilage destruction Pro-inflammatory cytokinesTài liệu có liên quan:
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