Differential methylation patterns in lean and obese non-alcoholic steatohepatitis-associated hepatocellular carcinoma
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Nonalcoholic fatty liver disease affects about 24% of the world’s population and may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma (HCC). While more common in those that are obese, NASH-HCC can develop in lean individuals. The mechanisms by which HCC develops and the role of epigenetic changes in the context of obesity and normal weight are not well understood.
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Liver cancer Non-alcoholic fatty liver disease Nonalcoholic steatohepatitis Wnt-signaling pathways Non-obese miceTài liệu có liên quan:
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