High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/ regulatory T-cell infiltration
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Relationship between cancer cell glycolysis and the landscape of tumor immune microenvironment in human cancers was investigated. Forty-one fresh lung adenocarcinoma (ADC) tissues were analyzed using flow cytometry for comprehensive immunoprotein. Formalin-fixed tissues were immunostained for hexokinase-2 (HK2) to assess cancer cell glycolysis.
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Hexokinase-2 Tumor microenvironment Tumor-infiltrating lymphocytes CD8+T-cell to Treg ratioTài liệu có liên quan:
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