Oral squamous cell carcinoma (OSCC) is a common malignant tumor associated with poor prognosis. MicroRNAs (miRNAs) play crucial regulatory roles in the cancer development. However, the role of miRNAs in OSCC development and progression is not well understood. Methods We sought to establish a dynamic Chinese hamster OSCC animal model, construct miRNA differential expression profiles of its occurrence and development, predict its targets, and perform functional analysis and validation in vitro.
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Screening and identification of miR181a-5p in oral squamous cell carcinoma and functional verification in vivo and in vitro
Screening and identification of miR181a-5p in oral squamous cell carcinoma and functional verification in vivo and in vitro
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BMC Cancer Chinese hamster animal model Functional analysis Nude mouse tumorigenic model Colony formation Cell cycle-related genesTài liệu có liên quan:
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