Study on optimization of ternary complex of piroxicam-β-cyclodextrin-lysine inclusion in supercritical CO2
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In this study, piroxicam/β-cyclodextrin complexes are prepared in supercritical carbon dioxide (SC-CO2 ) in the solid state and the process was optimized using response surface methodology (RSM). UV-Vis spectroscopy, differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), and dissolution profile in water were used to characterized the complex under optimized temperature, residence time, moisture, and ternary agent.
Nội dung trích xuất từ tài liệu:
Study on optimization of ternary complex of piroxicam-β-cyclodextrin-lysine inclusion in supercritical CO2
Nội dung trích xuất từ tài liệu:
Study on optimization of ternary complex of piroxicam-β-cyclodextrin-lysine inclusion in supercritical CO2
Tìm kiếm theo từ khóa liên quan:
Ternary complex of piroxicam-β-cyclodextrin-lysine inclusion in supercritical CO2 CO2 supercritical fluid Piroxicam solubility Differential scanning calorimetry Fourier-transform infrared spectroscopyTài liệu có liên quan:
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