Synthesis and cytotoxic activity of some 2-(2,3-dioxo-2,3-dihydro-1H -indol-1-yl)acetamide derivatives
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Isatin, 1H -indoline-2,3-dione, an endogenous compound, is also a synthetically versatile molecule that possesses a diversity of biological activities including anticonvulsant, antibacterial, antifungal, antiviral, anticancer, and cytotoxic properties. Based on the promising cytotoxic activity studies on N -substituted isatin derivatives, a series of 18 derivatives of 2-(2,3-dioxo-2,3-dihydro-1H -indol-1-yl)-N -phenylacetamide were designed, synthesized, and characterized according to their analytical and spectral data.
Nội dung trích xuất từ tài liệu:
Synthesis and cytotoxic activity of some 2-(2,3-dioxo-2,3-dihydro-1H -indol-1-yl)acetamide derivatives
Nội dung trích xuất từ tài liệu:
Synthesis and cytotoxic activity of some 2-(2,3-dioxo-2,3-dihydro-1H -indol-1-yl)acetamide derivatives
Tìm kiếm theo từ khóa liên quan:
Journal of Chemistry Cytotoxic activity HEK293 cell lines Carboxylesterase inhibitor activities N -phenylisatin-1-acetamide derivativesTài liệu có liên quan:
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