Bài thuyết trình tiếng Anh đề tài: Respiratory Acidosis

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Bài thuyết trình tiếng Anh đề tài: Respiratory AcidosisRespiratoryAcidosisDone by : Ibrahim Ali Al-SayeghID# 2021040084Supervised by : Dr. Ibrahim Saeed RESPIRATORYACIDOSISDefinition: APrimaryincreaseinarterialPaCO2 leadingtodecreaseinarterialpH. ItcouldbeAcuteorChronic :CausesEither : alveolar hypoventilationOr V/P mismatching Alveolarhypoventilation : Respiratory Center suppression-1 Can be suppressed by many factors like : drugs Neuromuscular Junction : Ex : mysthenia gravies-2 Respiratory Muscles: Ex : myopathy-3 Pleural Cavity: Ex : pneumothorax-4 :Lung Parenchyma and Airways-5 ( Ex: obstructive lung disease ( BA & COPD Alveolar hypoventilation V/Pmismatching pulmonary embolism Pneumonia Acute respiratory distress syndrome Collapsing of alveoli fibrosis VentilationPerfusionMismatching AlveolarHypoventilation RESPIRATORYACIDOSISThe Value of “A-a” Gradient: Calculation:1. paCo2 X 1.2 = X2. 150 – X = “A”3. A (alveolar O2) – a (arterial O2) = A-a gradient. Normal A-a Gradient = Up to 15 mmHg. High A-a Gradient Vent Perfusion mismatching. Normal A-a Gradient Alveolar Hypoventilation. ABGfindinginrepiratoryacidosis PH PCO2 HCO3 Acute Decrease normal d increased Chronic o r Normal compensated increased increased :Clinicalmanifestation Signs and symptoms are related to the degree and duration of respiratory acidosis . Precipitous rise in PCo2 can lead to : Confusion , anexity , psychosis , flapping tremor , seizure . Signs of catecholamines release : diaporesis , increase heart rate and high cardiac output, flushing. Coma in PCo2 > 60 mmHg ( Co2 narcosis) Signs of chronic hypercapnia : Fatigue , lethargy in addition to finding in acute hypercapnia . :Treatment Treatment of repiratory acidosis aimed primarily at : Correction of underlying cause ( COPD,asthma, pulmonary embolism ….) And Ensuring adequate ventilation :Rolesinmanagement in management of patient with respiratory acidosis >>> we don’t give him 100% oxygen to not suppress the respiratory center . Also , sedatives , narcotics are contraindicated unless we will put the pt. on ventilator . Bicarbonate therapy considered when PH fall below 7.1 Rapid and complete correction may lead to posthypercapnic alkhalosis > specially in patient with chronic respiratory acidosis .