Summary of the PhD thesis Animal genetics and preeding: The association between polymorphismsof some cadidate genes and growth performance, backfat thickness and intramuscular fat traits in duroc pigs

The aim of the thesis research: Determine the polymorphisms of MC4R, PIT1, GH, LEP, PIK3C3 genes and their association with the traits of growth performance, backfat thickness, and reproductive performance in Duroc pigs; determine the polymorphism of ADRB3, ACSL4, FABP3, PLIN2 genes and the association with the intramuscular fatin Duroc pigs; select the Duroc pig line in the direction of growth performance using the support from genotype information.
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Summary of the PhD thesis Animal genetics and preeding: The association between polymorphismsof some cadidate genes and growth performance, backfat thickness and intramuscular fat traits in duroc pigsMINISTRY OF EDUCATION AND MINISTRY OF AGRICULTURE AND TRAINING RURAL DEVELOPMENT NATIONAL INSTITUTE OF ANIMAL SCIENCE HOANG THI THUY THE ASSOCIATION BETWEEN POLYMORPHISMSOF SOME CADIDATE GENES AND GROWTH PERFORMANCE, BACKFATTHICKNESS AND INTRAMUSCULAR FAT TRAITS IN DUROC PIGS SUMMARY OF THE PhD THESIS Majors: Animal Genetics and Breeding Code: 9. 62. 01. 08 Hanoi - 2021 Research completed at:National Institute of Animal Science VIỆN CHĂN NUÔI Scientific supervisors: 1- Ph.D Pham Doan Lan 2- Ph.D Doan Van Soan 1. TS. Phạm Doãn Lân 2. TS. Đoàn Văn Soạn The first reviewer: Assoc. Prof. Ph.D. Dong Van Quyen The second reviewer: Assoc. Prof. Ph.D. Phan Xuan Hao The third reviewer:Ph.D. Nguyen Van Hau This thesis will be defended at the Institute-level Phd Thesis Evaluation Council,which will be met at National Institute of Animal Science, Thuy Phuong, Bac Tu Liem,Hanoi. At, 2021 Thesis can be found at the library: 1. Library of National Institute of Animal Science 2. National Library of Vietnam 2 LIST OF SCIENTIFIC PUBLICATIONS RELATED TO THE THESIS 1. Hoang Thi Thuy, Giang Thi Thanh Nhan, Pham Thi Phuong Mai, Tran Thi Thu Thuy, Le Quang Nam,Doan Phuong Thuy, Nguyen Van Hung, Tran Xuan Manh, Doan Van Soan and Pham Doan Lan. 2019.Associations of some candidate genes polymorphisms with growth traits in Duroc pig. Livestock Research forRural Development, Volume 31(10), October. 2. Hoang Thi Thuy, Giang Thi Thanh Nhan, Pham Thi Phuong Mai, Tran Thi Thu Thuy, Le Quang Nam,Doan Phuong Thuy, Nguyen Van Hung, Tran Xuan Manh, Doan Van Soan and Pham Doan Lan. 2021. Theassociation between polymorphisms of some candidate genes and the growth and backfat thickness of Duroc pigover two generations. Journal of Science and Technology of Livestock. Number 264: 1 - 7. 3. Hoang Thi Thuy, Pham Thu Thao, Giang Thi Thanh Nhan, Nguyen Van Hung, Tran Xuan Manh,Doan Van Soan and Pham Doan Lan. 2021. Polymorphisms of candidate genes and their association withintramuscular fat in Duroc Pig. Journal of Livestock Science and Technology, Institute of Livestock Production.February issue. Vol 120: 90 - 98. 3 PREFACE1. The necessary requirements of the thesis In recent years, the rapid development of molecular genetics hashelped the selection oflivestock breedsfaster, more accurate and more efficient. Many candidate genes related to growth and meat quality had been studied andproposed to be used for selection programs supported by molecular markers such as MC4R,PIT1, GH, LEP, PIK3C3, FABP3, ADRB3, PLIN2, ACSL4genes.However, the relationshipbetween gene polymorphisms and traits depended on the characteristics or genetic nature ofeach pig population at each production facility. Therefore, to apply genes to support selectionof livestock breeds for each desired trait, it was necessary to conduct research to evaluate theassociation of candidate genes on the population which was selected. Duroc pigs were one of the foreign pig breeds that had the ability to gain weightquickly, good meat quality (soft meat due to fat mixed with lean) and high lean percentage.Therefore, in Vietnam, Duroc pigs were used in lean herd programs, which partly improvedthe productivity and quality of meat for the pork industry. On the other hand, many studiesshowed that the weight gain in Duroc pigs in Vietnam was not superior to the weight gain inDuroc pigs of some developed countries. Therefore, how to improve the ability to increaseweight, backfat thickness and the quality of meat to promote the pork industry was becomingan important research direction. In order to had a scientific basis for the application of genetic markers to support theselection and improvement the ability to increase weight and meat quality of Duroc pigs fed atDabaco Nuclear Pig Breeding Co., Ltd., I researched the topicThe association betweenpolymorphisms of some candidate genes and growth performance, backfat thickness andintramuscular fat traits in Duroc pigs.2. The aim of the thesis research Determine the polymorphisms of MC4R, PIT1, GH, LEP, PIK3C3 genes and theirassociation with the traits of growth performance, backfat thickness, and reprod ...